Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines

DNA Demethylating Activity of Hydralazine in Cancer Cell Lines

E de la Cruz-Hernandez, E Perez-Cardenas, L Taja-Chayeb, A Chavez-Blanco, C TrejoBecerril, J Trujillo, JL Medina-Franco, A Dueñas-Gonzalez* Unidad de Investigación en Cáncer, Instituto de Investigaciones Biomédicas, UNAM, Mexico City, and Instituto Nacional de Cancerología, Mexico City, ISSEMYM Cancer Center, Toluca, Mexico. Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway...

Metastatic Renal cell Carcinoma Presenting as a clear-cell Tumor in Tongue: A Case Report

Introduction: Metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. The most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. Renal cell carcinoma accounts for nearly 3% of all adult malignancies. It usually metastasizes to the lungs,...

Sarcomatoid Transrormation of Chromophobe Renal Cell Carcinoma

An Unusual Case Report: Occurrence of Renal Cell Carcinoma, Basal Cell Carcinoma and Chronic Lymphocytic Leukemia in a Case of Papillary Thyroid Carcinoma Treated with Radioactive Iodine

The standard therapy for thyroid cancer is total or near total thyroidectomy, followed by the administration of radioactive iodine for remnant ablation or residual disease. Patients with radioiodine therapy are predisposed to second malignant neoplasms in organs such as central nervous system (CNS), breast, prostate, kidney, bone marrow, salivary gland, and digestive tract. Exposure to carcinog...

Prognostic value of p53 in renal cell carcinoma

Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...